WebMay 25, 2024 · The majority of patients underwent surgery followed by adjuvant Anthracycline and Taxane based induction chemotherapy followed by HDC-ASCT for consolidation. The HDC regimen consisted of Carmustine 600 mg/m 2, Cyclophosphamide 5.6gm/ m 2 and Cisplatin 165mg/ m 2 (STAMP 1 regimen). Four patients received … WebNov 5, 2024 · Our institutional approach has focused on developing potentially more active HDC regimens, and on consideration of post-ASCT consolidation RT, especially for pts …
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WebApr 14, 2024 · Participants deemed ineligible to receive HDC followed by ASCT based on the treating physician's assessment and meeting the following criteria: Age ≥ 18 years and. Prior ASCT (as first-line consolidation) or; Haematopoietic Cell Transplantation-specific Comorbidity Index (HCT-CI) > 3. Age ≥ 65 years and 1 of the criteria below: WebMar 31, 2016 · The most relevant alternatives to WBRT are high-dose chemotherapy supported by autologous stem cell transplantation (HDC/ASCT) or nonmyeloablative chemotherapy, the former supported by several single-arm phase 2 trials. Moreover, HDC/ASCT is the only strategy that is assessed in comparison with WBRT in ongoing … WebApr 10, 2024 · HDC-ASCT protocols adapted to older age are feasible in selected patients with promising results [70]. Maintenance treatment is another strategy, using agents well tolerated in long-term use and without cumulative toxicity such as temozolomide, procarbazine, rituximab, lenalidomide, ibrutinib and immunotherapy with immune … jewish soup names