Rna-binding proteins and cancer metastasis
WebApr 12, 2024 · Heterogeneous nuclear ribonucleoprotein A/B (hnRNPAB) is an RNA binding protein that is closely associated with the biological function and metabolism of RNA, which is involved in the malignant transformation of various tumor cells. However, the role and mechanisms of hnRNPAB in non‑small cell lung cancer (NSCLC) are still unclear. WebSep 15, 2024 · RNA-binding proteins are frequently dysregulated in human cancer and able to modulate tumor cell proliferation as well as tumor metastasis through post-transcriptional regulation on target genes. Abnormal DNA damage response and repair mechanism are closely related to genome instability and cell transformation.
Rna-binding proteins and cancer metastasis
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WebThe S taufen 1 ‐dependent cell cycle regulon or how a misregulated RNA‐ binding protein leads to cancer. Biological Reviews, 96(5), 2192–2208. doi:10.1111/brv.12749 WebApr 14, 2024 · B-cell lymphoma 6 (BCL6) is a transcription repressor that plays a tumor suppressor or promoting role in various tumors. However, its function and molecular …
WebSep 17, 2024 · Nearly 7.5% of all human protein-coding genes have been assigned to the class of RNA-binding proteins (RBPs), and over the past decade, RBPs have been … WebRNA-binding proteins (RBPs) are key players in post-transcriptional events. The combination of versatility of their RNA-binding domains with structural flexibility enables RBPs to …
WebLoss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer . The mechanisms through which cancer cells lock in … WebJan 21, 2024 · Ovarian cancer (OC), an important cause of cancer-related death in women worldwide, is one of the most malignant cancers and is characterized by a poor …
WebNov 1, 2024 · RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally influencing all manner of RNA biology, including alternative splicing (AS), …
WebA new model of DDX21 is elucidated in regulating CRC metastasis via phase separation, which is significantly correlated with poor survival outcomes of stage III and IV CRC … friedberger warte apotheke faxWebMembers of this family directly target the metastasis-promoting protein, WAVE3, to inhibit PCa cell invasion. 59 These miRNAs also target the E-cadherin transcriptional repressors, … fat wheel electric bicycleWebApr 11, 2024 · RNA-binding proteins (RBPs) are emerging as important regulators of pathogenesis, including cancer. Here we reveal that the recently characterised RBPs … friedberg family medicine after hoursWebApr 12, 2024 · RNA binding proteins (RBPs) are necessary for a range of cellular functions—including cell transport, localization, development ... contains over 70 miR-7 … friedberg disease footWebApr 7, 2024 · RNA binding proteins (RBPs) contributes to cancer progression, but the underlying mechanism reminds unclear. Here, we find that DDX21, a representative RBP, is highly expressed in colorectal ... fat wheel cycleWebRNA binding proteins (RBPs) are pivotal post-transcriptional regulators. RNPC1, an RBP, acts as a tumor suppressor through binding and regulating the expression of target genes … fat wheeled motorcycleWebApr 11, 2024 · The HNRNPF/H RNA binding proteins are regulators of RNA maturation, particularly alternative splicing. Recent studies have highlighted the discovery of … fat wheeled electric bikes