Webb18 dec. 2024 · Pomegranate. Pomegranate juice and seeds both have powerful antioxidant properties that may improve the function of HDL cholesterol. This protective cholesterol may boost the reverse cholesterol transport, or “vacuum cleaner” function in arteries, that may reverse CAD. In studies of mice, pomegranates can reduce atherosclerosis although … Webb10 maj 2024 · Sweet orange (citrus sinensis) may inhibit OATP, which helps mediate hepatic uptake and facilitates statin metabolism. Tangerines are related to sweet …
Interaction between simvastatin and cranberry juice in an elder
Webb20 dec. 2024 · Mean plasma concentration-time profiles of (A) simvastatin and (B) simvastatin acid in rats after oral administration of 20 mg/kg simvastatin alone or concomitant with 1 mg/kg pomelo juice twice ... WebbSince sweet orange juice shows no effect on CYP3A4, clinically significant interactions have been exhibited by this juice, mediated through OATPs. Its interactions were found more significant than those for grapefruit juice. The plasma levels of various OATP2B1 substrates such as atenolol and fexofenadine were markedly decreased in healthy ... does chat avenue save their chat logs
(PDF) Effect of Pomelo Juice on the Pharmacokinetics of Simvastatin …
Webb6 apr. 2024 · As a result, “the drug stays in the blood and accumulates, increasing the risk of side effects such as muscle pain.” Of the statins, atorvastatin, lovastatin and simvastatin (common brand names Lipitor, Altoprev/Mevacor and Zocor) are the most problematic as far as grapefruit juice goes. WebbResearch shows that other fruit juices as well as whole fruit, fruit pulp and fruit extracts have also been associated with altered drug metabolism and subsequent interactions. Variability in fruit strains, environmental conditions, processing procedures, and patient factors make it difficult to predict whether a fruit or fruit product will lead to a medicine … WebbThere is no absolute consensus about how much grapefruit a person can safely eat while taking statins, but Dr. Hazen takes a measured approach with his patients. “I personally tell my folks who ... eystreem scary survival ep 41