site stats

Sperm associated antigen 6

WebDec 20, 2024 · Accumulated evidence shows that sperm-associated antigen 6 (SPAG6) gene has multiple biological functions. It maintains the normal function of a variety of cells including ciliary/flagellar biogenesis and polarization, neurogenesis, and neuronal migration. Moreover, SPAG6 is found to be critically involved in auditory transduction and the ... WebMay 12, 2016 · Sperm associated antigen 6 (SPAG6), a component of the central apparatus of the “9 + 2” axoneme, plays a central role in ciliary and flagellar motility; but, its contribution to adaptive immunity...

Impaired immunological synapse in sperm associated …

WebOct 30, 2024 · Sperm-associated antigen 5 (SPAG5) is a mitotic spindle-associated protein that is involved in various biological processes in cervical cancer and bladder urothelial … WebSep 22, 2024 · Sperm-associated antigen 6 (SPAG6) is an ortholog of chlamydia PF16, located at the chromosomal region 10p12.2 . SPAG6 was originally identified in human testicular tissues and plays a role in regulating germ cell … smo earth https://hypnauticyacht.com

Entry - *605730 - SPERM-ASSOCIATED ANTIGEN 6; SPAG6 - OMIM

WebJan 27, 2024 · The mouse sperm-associated antigen 6 (Spag6) gene, the ortholog of Chlamydomonas PF16, encodes a 55.3-kDa polypeptide that is a component of the axoneme central apparatus of flagella and motile cilia. It interacts with the central pair microtubules and is required for their stability in the axoneme (7, 8). WebApr 12, 2024 · The claudin 18.2 (CLDN18.2) antigen is frequently expressed in malignant tumors, including pancreatic ductal adenocarcinoma (PDAC). Although CLDN18.2-targeted CAR-T cells demonstrated some therapeutic efficacy in PDAC patients, further improvement is needed. One of the major obstacles might be the abundant cancer-associated … WebDec 8, 2024 · SPAG6 sperm associated antigen 6 Gene ID: 9576, updated on 8-Dec-2024 Gene type: protein coding Also known as: pf16; CT141; FAP194; CFAP194; Repro-SA-1 See all available tests in GTR for this gene Go to complete Gene record for SPAG6 Go to Variation Viewer for SPAG6 variants Summary smof 1600kcal

Impaired immunological synapse in sperm associated antigen 6 (SPAG6 …

Category:The sperm-associated antigen 6 interactome and its role in ...

Tags:Sperm associated antigen 6

Sperm associated antigen 6

Sperm-associated antigen 6 (Spag6) mutation leads to vestibular ...

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and … See more Sperm-associated antigen 6 is a protein that in humans is encoded by the SPAG6 gene. See more • Diekman AB, Herr JC (January 1997). "Sperm antigens and their use in the development of an immunocontraceptive". American Journal of Reproductive Immunology. 37 (1): 111–7. doi:10.1111/j.1600-0897.1997.tb00199.x. PMID See more WebMammalian SPAG6, the orthologue of Chlamydomonas reinhardtii PF16, is a component of the central apparatus of the '9 + 2' axoneme that controls ciliary/flagellar motility, …

Sperm associated antigen 6

Did you know?

WebOct 21, 2014 · SPAG6, an axoneme central apparatus protein, is essential for function of ependymal cell cilia and sperm flagella. A significant number of Spag6 -deficient mice die …

WebDec 8, 2024 · sperm associated antigen 6. Gene ID: 9576, updated on 8-Dec-2024. Gene type: protein coding. Also known as: pf16; CT141; FAP194; CFAP194; Repro-SA-1. See all … WebNov 20, 2015 · Sperm Associated Antigen 6 (SPAG6) Regulates Fibroblast Cell Growth, Morphology, Migration and Ciliogenesis Scientific Reports Open Access Published: 20 …

WebOct 21, 2014 · SPAG6, an axoneme central apparatus protein, is essential for function of ependymal cell cilia and sperm flagella. A significant number of Spag6-deficient mice die with hydrocephalus, and surviving males are sterile because of sperm motility defects. In further exploring the ciliary dysfunction in Spag6-null mice, we discovered that cilia beat … WebOct 30, 2024 · Sperm associated antigens (SPAGs) are specific proteins in terms of performance and evolution, that have common expressions in the testes or sperm cells. Moreover, the humoral immune...

WebDec 20, 2024 · The sperm-associated antigen 6 (SPAG6), also known as CT141, repro-sa-1, RP11-301N24.4, and pf16, was identified as a cancer-testis antigen (CTA) and is encoded …

WebJul 1, 2009 · Sperm associated antigen 6 (SPAG6), a sperm protein, has been linked with sperm flagellar motility and structural integrity of the axoneme central apparatus of mature sperm in mice and humans. Sperm proteins especially those associated with sperm motility are potential biochemical targets for therapeutic or contraceptive management. Detection ... smoed california all starsWebAug 1, 2024 · Sperm-associated antigen 6 (SPAG6) is the mammalian orthologue of Chlamydomonas PF16, an axonemal central pair protein involved in flagellar motility. In mice, two Spag6 genes have been identified. river report californiaWebSperm-associated antigen 6 is a protein that in humans is encoded by the SPAG6 gene.[4][5] For faster navigation, this Iframe is preloading the Wikiwand page for Sperm-associated … smoething rattling in macbook fanWebsperm-associated antigen 6; Background. The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the ... river rentals marylandWebDec 1, 2024 · The mouse sperm-associated antigen 6 ( Spag6) gene, the orthologue of Chlamydomonas PF16, encodes a 55.3-kDa polypeptide that is a component of the … river report curtis miramichi outfittersWebImproved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. smof 1100WebDec 1, 2024 · The mouse sperm-associated antigen 6 ( Spag6) gene, the orthologue of Chlamydomonas PF16, encodes a 55.3-kDa polypeptide that is a component of the axoneme central apparatus of flagella and motile cilia.1 SPAG6 is ubiquitously expressed in tissue and organs containing ciliated cells, such as in the central nervous system, respiratory … smo energy reviews